What is the GATTAscope project?

Fluorescence microscopy is our daily but not less fascinating tool to achieve new insights in biology and various other disciplines. Recent developments even pushed the limits of imaging far beyond the limits of what we took for granted over decades. We detect fluorophores on the single molecule level and super-resolution microscopy increased the resolution by magnitudes. Milestones in research – and not for nothing awarded by the Nobel prize.

But all the advantages come along with a new complexity of the systems, new demands to the samples and a challenge for ourselves. Even though commercial setups are enabling state-of-the-art imaging in highly sophisticated systems, the parameter space of settings is huge and a deep understanding of the microscope and its interaction with the sample is mandatory to successfully exploit the full capabilities of the new techniques.

But what are the components in a microscope?

And how do they interact?

How can I check if my system works as expected?

To answer these questions, we started the GATTAscope project. Feel welcome to browse through our website, find information about building your own TIRF microscope, see components and their interaction, learn more in tutorials, videos and blogs.

Welcome to GATTAscope!